KARISMA Rh Collagen®

KARISMA Rh Collagen® is an internationally recognised injectable medical device classified as MD Class III. It is the world’s first pure injectable Recombinant Human Collagen Type 1 (Rh Collagen), designed to naturally restore pre-ageing conditions by rejuvenating the extracellular matrix. Our unique formulation, which includes a patented natural human collagen precursor (collagen polypeptidic α 1 chain R), ensures a calibrated dosage that promotes the long-lasting production of type I collagen in dermal fibroblasts.

In Thailand, KARISMA is registered as an MD Class 4 device under Rule 14 of Thai law, registration No. 67-2-1-2-0010070, and may only be purchased and utilised by qualified medical professionals or registered medical establishments in accordance with Thai FDA regulations. Should you be interested in KARISMA Rh Collagen, please complete the following form: https://forms.gle/Lj6ecyj1KBXQz7Jc7

KARISMA Rh Collagen® สามารถซื้อและใช้งานได้โดยแพทย์ผู้เชี่ยวชาญหรือสถานพยาบาลที่จดทะเบียนตามข้อกำหนดของอย.ไทยเท่านั้น หากท่านสนใจ โปรดกรอกแบบฟอร์มต่อไปนี้: https://forms.gle/Lj6ecyj1KBXQz7Jc7 

KARISMA Rh Collagen® contains:
1. Collagen Polypeptidic α1 Chain (Rh Collagen) 
– The polypeptidic α1 chain R increase the synthesis of collagen type I peptide in humane dermal fibroblasts.
– Polypeptidic α1 chain R stimulates and facilitates the winding of procollagen triple helix chains.

2. High Molecular Weight Hyaluronic Acid (HMW – HA)
– Hydration and maintenance of an environment favorable to the proliferation and metabolism of fibroblasts.
– Antioxidant action and increase skin elasticity .

3. Carboxymethylcellulose (CMC)
– It inhibits the action of the hyaluronidase enzyme.
– Preserves endogenous hyaluronic acid.
– Slows down the action of MMPs.